Categories
2-HYDROXYADENOSINE
- CAS: 1818-71-9
- Purity: 99%
- Quality Manufacturer Supply High Purity 99% 2-HYDROXYADENOSINE 1818-71-9 with Reasonable Price
Quality Manufacturer Supply High Purity 99% 2-HYDROXYADENOSINE 1818-71-9 with Reasonable Price
- Molecular Formula: C10H13N5O5
- Molecular Weight: 283.244
- Vapor Pressure: 2.83E-29mmHg at 25°C
- Melting Point: 237-241 °C(Solv: water (7732-18-5))
- Refractive Index: 1.955
- Boiling Point: 831oC at 760 mmHg
- PKA: 8.25±0.40(Predicted)
- Flash Point: 456.4oC
- PSA： 159.51000
- Density: 2.25 g/cm3
- LogP: -2.10550
2-HYDROXYADENOSINE(Cas 1818-71-9) Usage
InChI:InChI=1/C10H13N5O5/c11-7-4-8(14-10(19)13-7)15(2-12-4)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)
1818-71-9 Relevant articles
Nucleosides and nucleotides. XIII. Synthesis of thiopurine nucleosides from adenosine and guanosine derivatives by the sulfhydrolysis
Miura,Ueda
, p. 2064 - 2069 (1975)
-
Subsecond detection of physiological adenosine concentrations using fast-scan cyclic voltammetry
Swamy, B. E. Kumara,Venton, B. Jill
, p. 744 - 750 (2007)
Adenosine modulates blood flow and neuro...
-
Cramer,Schlingloff
, p. 3201,3203 (1964)
-
2-Substituted α,β-Methylene-ADP Derivatives: Potent Competitive Ecto-5′-nucleotidase (CD73) Inhibitors with Variable Binding Modes
Bhattarai, Sanjay,Pippel, Jan,Scaletti, Emma,Idris, Riham,Freundlieb, Marianne,Rolshoven, Georg,Renn, Christian,Lee, Sang-Yong,Abdelrahman, Aliaa,Zimmermann, Herbert,El-Tayeb, Ali,Müller, Christa E.,Str?ter, Norbert
supporting information, p. 2941 - 2957 (2020/04/10)
CD73 inhibitors are promising drugs for ...
Novel isoguanine derivative of unlocked nucleic acid—Investigations of thermodynamics and biological potential of modified thrombin binding aptamer
Kotkowiak, Weronika,Czapik, Tomasz,Pasternak, Anna
, (2018/05/30)
Thrombin binding aptamer (TBA), is a sho...
High-throughput five minute microwave accelerated glycosylation approach to the synthesis of nucleoside libraries
Bookser, Brett C.,Raffaele, Nicholas B.
, p. 173 - 179 (2007/10/03)
The Vorbrueggen glycosylation reaction w...
1818-71-9 Process route
-
-
2096-10-8
adenosine-2-amine
-
-
146-78-1
2-fluoroadenosine
-
-
1818-71-9
isoguanosine
| Conditions | Yield |
|---|---|
|
With
pyridine; potassium nitrite; hydrogen fluoride;
at -11 - -6 ℃;
for 1h;
|
80.3%
|
-
-
2096-10-8
adenosine-2-amine
-
-
1818-71-9
1,2-dihydro-2-oxoadenosine
| Conditions | Yield |
|---|---|
|
With
acetic acid; sodium nitrite;
In
water;
at 50 ℃;
for 0.0833333h;
|
91.4%
|
|
With
acetic acid; sodium nitrite;
In
water;
at 50 ℃;
for 0.0833333h;
|
90%
|
1818-71-9 Upstream products
-
2096-10-8
adenosine-2-amine
-
17651-21-7
2',3'-O-Isopropylideneisoguanosine
-
35109-88-7
2-iodoadenosine
-
86187-42-0
2-hydroxy-6-amino-9-(2,3,5-tri-O-trimethylsilyl-β-D-ribofuranosyl)purine
1818-71-9 Downstream products
-
129285-58-1
N3 ,5'-anhydroisoguanosine
-
864737-30-4
5'-deoxy-5'-[(4-methoxyphenyl)thio]isoguanosine
-
864737-32-6
N6 -[(dimethylamino)methylene]-5'-deoxy-5'-[(4-methoxyphenyl)thio]isoguanosine
-
3373-53-3
isoguanine (6-amino-1H-purin-2(9H)-one)
