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Ranolazine
- CAS: 142387-99-3
- Purity: 99%
- Reputable factory supply Ranolazine 142387-99-3 in stock with high standard
Quality products?make an important contribution to long-term revenue and profitability. Reputable factory supply Ranolazine 142387-99-3 in stock with high standard
1.What is the Ranolazine ?
Ranolazine is for the treatment of chronic angina. It should be used in combination with amlodipine, beta-blockers or nitrates.
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162712-35-8
CVT-2513
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1131-01-7
2-chloro-N-(2,6-dimethylphenyl)acetamide
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95635-55-5,142387-99-3
Ranolazine
| Conditions | Yield |
|---|---|
|
With
potassium carbonate; sodium iodide;
In
N,N-dimethyl-formamide;
at 30 - 35 ℃;
for 18h;
|
34%
|
|
With
potassium carbonate;
sodium iodide;
In
N,N-dimethyl-formamide;
at 30 - 35 ℃;
for 18h;
|
|
|
In
N,N-dimethyl-formamide;
at 90 ℃;
for 12h;
|
-
-
ranolazine dihydrochloride
-
-
95635-55-5,142387-99-3
Ranolazine
| Conditions | Yield |
|---|---|
|
With
sodium hydroxide;
In
benzene;
|
|
|
With
ammonia;
In
water; acetone;
for 2h;
|
|
|
With
sodium hydroxide;
In
dichloromethane; water;
at 25 - 35 ℃;
|
2.What is the CAS number for Ranolazine ?
The CAS number of Ranolazine is 142387-99-3.
More information of Ranolazine 142387-99-3 are:
|
CAS?Number |
142387-99-3 |
|
Density |
1.174g/cm3 |
|
Boiling Point |
624.1°C at 760 mmHg |
|
Flash Point |
331.2°C |
|
Vapor Pressure |
1.94E-16mmHg at 25°C |
|
Refractive Index |
1.585 |
|
HS CODE |
2933990090 |
|
PSA |
74.27000 |
|
LogP |
2.25680 |
3.What are another words for Ranolazine ?
Synonyms?for?Ranolazine 142387-99-3:Ranolazine intermediate
4.What is the molecular formula of Ranolazine?
The chemical formula of ?Ranolazine is?C24 H33 N3 O4 which containing 24 Carbon atoms,33 Hydrogen atoms,3 Nitrogen atoms and 4 Oxygen atoms,and the molecular weight of??Ranolazine?is 427.544.
5.What is Ranolazine (142387-99-3) used for?
Ranolazine (142387-99-3) is an FDA-approved drug used for the treatment of chronic angina. It inhibits the late inward sodium current in heart muscle leading to decreased intracellular calcium levels.1?Ranolazine blocks Nav 1.4, 1.5, 1.7 and 1.8 (IC50‘s = 2.42, 6.22, 1.72(10.33), 21.53 μM respectively.
InChI:InChI=1/C24H33N3O4/c1-18-7-6-8-19(2)24(18)25-23(29)16-27-13-11-26(12-14-27)15-20(28)17-31-22-10-5-4-9-21(22)30-3/h4-10,20,28H,11-17H2,1-3H3,(H,25,29)
Relevant articles related to Ranolazine:
|
Article |
Source |
|
An efficient synthesis of 1-(2-Methoxyphenoxy)-2,3-epoxypropane: Key intermediate of β-adrenoblockers |
Madivada, Lokeswara Rao,Anumala, Raghupathi Reddy,Gilla, Goverdhan,Kagga, Mukkanti,Bandichhor, Rakeshwar , p. 1660 - 1664 (2012) |
|
In silico approach towards lipase mediated chemoenzymatic synthesis of (S)-ranolazine, as an anti-anginal drug |
Sawant, Ganesh,Ghosh, Saptarshi,Banesh, Sooram,Bhaumik, Jayeeta,Chand Banerjee, Uttam , p. 49150 - 49157 (2016/06/09) |
6.Buy Ranolazine with the best price .
Neworld Chemical Co., Ltd Shanghai is a quality supplier of Ranolazine. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Ranolazine 142387-99-3.
