Pharmaceutical

1-ACETYLPYRROLIDINE

  • CAS: 4030-18-6
  • Purity: 99%
  • Quality Factory Supply 99% Pure 1-ACETYLPYRROLIDINE 4030-18-6 with Efficient Delivery
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Quality Factory Supply 99% Pure 1-ACETYLPYRROLIDINE 4030-18-6 with Efficient Delivery

  • Molecular Formula:C6H11NO
  • Molecular Weight:113.159
  • Vapor Pressure:0.176mmHg at 25°C 
  • Refractive Index:1.474 
  • Boiling Point:212.1 °C at 760 mmHg 
  • PKA:-0.41±0.20(Predicted) 
  • Flash Point:90.8 °C 
  • PSA:20.31000 
  • Density:1.019 g/cm3 
  • LogP:0.56660 

1-ACETYLPYRROLIDINE(Cas 4030-18-6) Usage

Synthesis Reference(s)

Tetrahedron, 52, p. 3403, 1996 DOI: 10.1016/0040-4020(96)00037-3Tetrahedron Letters, 35, p. 477, 1994 DOI: 10.1016/0040-4039(94)85085-2

InChI:InChI=1/C6H11NO/c1-6(8)7-4-2-3-5-7/h2-5H2,1H3

4030-18-6 Relevant articles

Amide rotation trajectories probed by symmetry

Kubyshkin, Vladimir,Budisa, Nediljko

, p. 6764 - 6772 (2017)

Amide rotation of peptidyl-prolyl fragme...

-

Zaugg et al.

, p. 2895,2896 (1960)

-

IrIII-Catalyzed direct syntheses of amides and esters using nitriles as acid equivalents: A photochemical pathway

Talukdar, Ranadeep

supporting information, p. 5303 - 5308 (2020/04/17)

An unprecedented IrIII[df(CF3)ppy]2(dtbb...

Environmentally benign decarboxylative: N-, O-, and S-Acetylations and acylations

Ghosh, Santanu,Purkait, Anisha,Jana, Chandan K.

supporting information, p. 8721 - 8727 (2020/12/30)

An operationally simple and general meth...

An organocatalytic C-C bond cleavage approach: A metal-free and peroxide-free facile method for the synthesis of amide derivatives

Vodnala, Nagaraju,Gujjarappa, Raghuram,Polina, Saibabu,Satheesh, Vanaparthi,Kaldhi, Dhananjaya,Kabi, Arup K.,Malakar, Chandi C.

supporting information, p. 20940 - 20944 (2020/12/31)

A facile organocatalytic approach has be...

Synthesis of Benzofurans and Benzoxazoles through a [3,3]-Sigmatropic Rearrangement: O-NHAc as a Multitasking Functional Group

Yan, Dingyuan,Jiang, Heming,Sun, Wenxue,Wei, Wei,Zhao, Jing,Zhang, Xinhao,Wu, Yun-Dong

supporting information, p. 1646 - 1653 (2019/09/04)

The synthesis of heterocycles relies hea...

4030-18-6 Process route

acetic acid
64-19-7,77671-22-8

acetic acid

1-[1-(phenylimino)ethyl]pyrrolidine

1-[1-(phenylimino)ethyl]pyrrolidine

N-nitrosopyrrolidine
930-55-2

N-nitrosopyrrolidine

N-(acetyl)pyrrolidine
4030-18-6

N-(acetyl)pyrrolidine

Phenyl acetate
122-79-2,34474-31-2

Phenyl acetate

phenol
108-95-2,27073-41-2

phenol

Conditions
Conditions Yield
With sodium hydroxide; sodium nitrite; In water; at 25 ℃; pH=3.7; Kinetics;
6-azido-2-hexanone
84702-77-2

6-azido-2-hexanone

N-(acetyl)pyrrolidine
4030-18-6

N-(acetyl)pyrrolidine

1-methylpiperidin-2-one
931-20-4

1-methylpiperidin-2-one

Conditions
Conditions Yield
With 1,1,1,3',3',3'-hexafluoro-propanol; titanium tetrachloride; In dichloromethane; at 25 ℃; for 24h; Time; Overall yield = 86 %; Overall yield = 0.039 g; Inert atmosphere;

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