Categories
3-CHLORO-D-ALANINE METHYL ESTER,HYDROCHLORIDE
- CAS: 112346-82-4
- Purity: 99%
- 3-CHLORO-D-ALANINE METHYL ESTER,HYDROCHLORIDE GMP Manufacturer Global Trade 112346-82-4 with Fast Delivery
3-CHLORO-D-ALANINE METHYL ESTER,HYDROCHLORIDE GMP Manufacturer Global Trade 112346-82-4 with Fast Delivery
- Molecular Formula: C4H8 Cl N O2 . Cl H
- Molecular Weight: 174.027
- Melting Point: 149-152℃
- PSA： 52.32000
- LogP: 1.22780
112346-82-4 Relevant articles
Synthesis method of R-3-methyl closerine hydrochloride
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Paragraph 0027; 0029; 0030; 0033; 0033; 0035, (2019/05/08)
The invention belongs to the field of dr...
112346-82-4 Process route
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67-56-1
methanol
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D-serine-N-carboxyanhydride
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112346-82-4
D-β-Chloroalanine methyl ester hydrochloride
| Conditions | Yield |
|---|---|
|
With
thionyl chloride;
at 25 ℃;
for 2h;
Temperature;
Green chemistry;
|
94.72%
|
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942123-68-4
(S)-2-(2,6-dioxo-3-(3,4,5-trimethoxybenzamido)piperidin-1-yl)acetic acid
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112346-82-4
D-β-Chloroalanine methyl ester hydrochloride
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942591-67-5
(S)-methyl 3-chloro-2-(2-((S)-2,6-dioxo-3-(3,4,5-trimethoxybenzamido)piperidin-1-yl)acetamido)propanoate
| Conditions | Yield |
|---|---|
|
(S)-2-(2,6-dioxo-3-(3,4,5-trimethoxybenzamido)piperidin-1-yl)acetic acid;
With
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
dichloromethane; dimethyl sulfoxide;
at 0 ℃;
D-β-Chloroalanine methyl ester hydrochloride;
With
triethylamine;
In
dichloromethane; dimethyl sulfoxide;
at 0 - 30 ℃;
|
68%
|
112346-82-4 Upstream products
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67-56-1
methanol
112346-82-4 Downstream products
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1758-77-6
(2S)-2-aziridinecarboxylic acid
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942591-67-5
(S)-methyl 3-chloro-2-(2-((S)-2,6-dioxo-3-(3,4,5-trimethoxybenzamido)piperidin-1-yl)acetamido)propanoate
